| Part I. Principles of Tissue Engineering: Scaffolds and Cells |
| 1 |
Course Overview/Clinical Problems for Tissue Engineering Solution
Introduction to Tissue Engineering in China (PDF)
Scaffolds: Introduction (PDF)
Scaffolds: Collagen-GAG Analogs of Extracellular Matrix (PDF) (Courtesy of Prof. Yannas. Used with permission.) |
Prof. Spector, MIT / Prof. Cui, Tsinghua University
Prof. Cui, Tsinghua University
Prof. Spector, MIT
Prof. Yannas, MIT |
| 2 |
Cells: Liver Cells (PDF) (Courtesy of Yingxin Xu and Qingling Feng. Used with permission.)
Scaffolds: Recent Advances in Tissue Engineering |
Yingxin Xu, M. D., and Qingling Feng Ph. D., Tsinghua University
Prof. Langer, MIT |
| 3 |
Scaffolds: Free-Form Manufacturing (PDF 1 of 2 - 2.6 MB)(PDF 2 of 2 - 1.8 MB) (Courtesy of Prof. Yongnian Yan. Used with permission.)
Scaffolds: Self-Assembled Proteins (PDF - 1.2 MB) (Courtesy of Dr. Shuguang Zhang. Used with permission.)
Review (PDF) |
Prof. Yan, Tsinghua University
Dr. S. Zhang, MIT
Prof. Spector, MIT |
| 4 |
Cells: Sources
Cells: Differentiated versus Stem Cells (PDF) |
Dr. C. Vacanti, MIT
Prof. Spector, MIT |
| Part II. Principles of Tissue Engineering: Cells and Regulators |
| 5 |
Scaffolds: Biomimetics Design (PDF)
Cells: Effects of Culture Conditions (PDF) (Courtesy of Dr. Lisa Freed. Used with permission.)
Review (PDF - 1.4 MB) |
Prof. Cui, Tsinghua University
Dr. L. Freed, MIT
Prof. Spector, MIT |
| 6 |
Quiz 1 |
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| 7 |
Regulators: Response to Mechanical Loading
Regulators: Roles of Environmental Factors |
Prof. Grodzinsky, MIT
Dr. Vunjak-Novakovic, MIT |
| 8 |
Cells: Embryonic and Other Stem Cell for Tissue Engineering
Gene Therapy
Regulators: Gene Transfer Wedded to Tissue Engineering (PDF) (Courtesy of Prof. Chris Evans. Used with permission.) |
Prof. Guo, Tsinghua University
Dr. Zhijie Chang, Tsinghua University
Prof. C. Evans, Harvard Medical School |
| Part III. Practice of Tissue Engineering: Clinical Applications |
| 9 |
Applications: Skin and Peripheral Nerve Regeneration (PDF - 1.0 MB) (Courtesy of Prof. Yannas. Used with permission.)
Nerve Repair (PDF - 1.3 MB) (Courtesy of Xiufang Zhang, Nanming Zhao, and Yandao Gong. Used with permission.)
Discussion: Clinical Applications (PDF) |
Prof. Yannas, MIT
Xiufang Zhang, Nanming Zhao, Yandao Gong, Tsinghua University
Prof. Spector, MIT |
| 10 |
Blood Vessels
Heart Valves
Discussion: Comparative Analysis of Tissue Engineering Strategies (PDF) |
Prof. Schoen, Harvard Medical School
Dr. W. B. Li, Tsinghua University
Prof. Spector, MIT |
| 11 |
Urinary Tissues/Organs
Clinical Applications and Underlying Principles |
Prof. Atala, MIT
Prof. Y. Cao, Tsinghua University |
| 12 |
Bone Regeneration (PDF) (Courtesy of Yu Xing M. D., Ph. D. Used with permission.)
Cartilage Repair (PDF - 1.0 MB)
Discussion: Review (PDF) |
Dr. Yu Xing, Tsinghua University, and Prof. Yan Wang, M. D., General Hospital of Peoples' Liberation Army
Prof. Spector, MIT
Prof. Spector, MIT |
| 13 |
Federal Regulatory Issues for Tissue Engineering Products in the U.S., China, and Other Countries (PDF)
Brain Repair
Review |
Prof. Spector, MIT
Prof. Cui, Tsinghua University
Prof. Spector, MIT / Prof. Cui, Tsinghua University |
| 14 |
Quiz 2 |
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